.Nature Medication, Posted online: 18 September 2024 doi:10.1038/ s41591-024-03300-3Genomic and epidemiologic analyses revealed that a novel reassortant viral descent of the Oropouche infection, which has been actually circulating in the western side Amazon location of Brazil for about a many years, is associated with the latest human outbreaks in between 2022 as well as 2024.